Vyvanse Side Effects

Vyvanse is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Vyvanse is used to treat attention deficit hyperactivity disorder (ADHD) in adults and in children who are at least 6 years old. It is used as a part of a total treatment program that may include psychological, educational, and social therapy.

Do not use Vyvanse if you have used an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam) within the past 14 days. Serious, life-threatening side effects can occur if you take Vyvanse before the MAO inhibitor has cleared from your body.

Do not use Vyvanse if you are allergic to lisdexamfetamine or if you have:

  • heart disease or moderate to severe high blood pressure (hypertension);
  • arteriosclerosis (hardening of the arteries);
  • overactive thyroid;
  • glaucoma;
  • severe anxiety, tension, or agitation; or
  • if you have a history of drug or alcohol addiction.

Some stimulants have caused sudden death in children and adolescents with serious heart problems or congenital heart defects. Before taking Vyvanse, tell your doctor if you have:

  • a congenital heart defect;
  • high blood pressure;
  • heart failure, heart rhythm disorder, or recent heart attack;
  • a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt;
  • epilepsy or other seizure disorder; or
  • tics (muscle twitches) or Tourette’s syndrome.

FDA pregnancy category C. It is not known whether Vyvanse will harm an unborn baby. It could cause premature birth, low birth weight, or withdrawal symptoms in a newborn if the mother takes Vyvanse during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Lisdexamfetamine can pass into breast milk and may harm a nursing baby. Do not use Vyvanse without telling your doctor if you are breast-feeding a baby.

Long-term use of Vyvanse can slow a child’s growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.

Do not give Vyvanse to a child younger than 6 years old without the advice of a doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Vyvanse: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • fast, pounding, or uneven heartbeats;
  • decreased blood pressure (feeling light-headed, fainting);
  • tremor, restlessness, hallucinations, unusual behavior, or motor tics (muscle twitches); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, seizure).

Less serious Vyvanse side effects may include:

  • loss of appetite, weight loss;
  • sleep problems (insomnia);
  • nausea, vomiting, stomach pain;
  • feeling irritable;
  • mild skin rash; or
  • dry mouth or an unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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