Renvela Side Effects

Renvela (sevelamer) is a phosphate binder. Sevelamer helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.

Renvela is used to reduce blood levels of phosphorus in people with chronic kidney disease who are on dialysis.

You should not take Renvela if you are allergic to sevelamer, or if you have a bowel obstruction.

To make sure you can safely take Renvela, tell your doctor if you have any of these other conditions:

  • trouble swallowing;
  • severe constipation;
  • a blockage in your intestines;
  • a stomach or intestinal disorder; or
  • if you have recently had stomach or intestinal surgery.

FDA pregnancy category C. It is not known whether Renvela will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sevelamer passes into breast milk or if it could harm a nursing baby. Do not use Renvela without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction to Renvela: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Renvela and call your doctor at once if you have a serious side effect such as:

  • black, bloody, or tarry stools;
  • constipation that gets worse or does not clear up;
  • severe constipation with stomach pain; or
  • fever, chills, body aches, flu symptoms.

Less serious Renvela side effects may include:

  • nausea, vomiting, stomach pain, loss of appetite;
  • upset stomach, gas, bloating;
  • diarrhea, mild constipation;
  • tired feeling;
  • itching; or
  • joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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