Neulasta Side Effects

Neulasta (pegfilgrastim) is a colony stimulating factor. It is a man-made form of a protein (amino acid) that stimulates the bone marrow and promotes the growth of white blood cells called neutrophils in your body. White blood cells help your body fight against infection.

Neulasta is used to prevent neutropenia, a lack of certain white blood cells caused by receiving chemotherapy.

You should not use Neulasta if you are allergic to pegfilgrastim or filgrastim (Neupogen).

To make sure you can safely use Neulasta, tell your doctor if you have any of these other conditions:

  • sickle cell disorder;
  • chronic myeloid leukemia;
  • myelodysplasia (also called “preleukemia”); or
  • if you are allergic to latex.

FDA pregnancy category C. It is not known whether Neulasta will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Neulasta.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Neulasta on the baby.

It is not known whether pegfilgrastim passes into breast milk or if it could harm a nursing baby. Do not use Neulasta without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction to Neulasta: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Neulasta and call your doctor at once if you have a serious side effect such as:

  • sudden or severe pain in your left upper stomach spreading up to your shoulder;
  • severe dizziness, skin rash, or flushing (warmth, redness, or tingly feeling);
  • rapid breathing or feeling short of breath;
  • signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, unusual weakness; or
  • bruising, swelling, pain, redness, or a hard lump where the injection was given.

Less serious Neulasta side effects may include:

  • bone pain;
  • pain in your arms or legs; or
  • bruising, swelling, pain, redness, or a hard lump where the injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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