Mirapex Side Effects

Mirapex (pramipexole) has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson’s disease.

Mirapex tablets are used to treat signs and symptoms of Parkinson’s disease and for the treatment of Restless Legs Syndrome (RLS).

Mirapex ER extended release tablets are used to treat the signs and symptoms of early and advanced Parkinson’s disease.

Mirapex may also be used for other purposes not listed in this medication guide.

You should not take Mirapex if your are allergic to pramipexole. Some people taking Mirapex have fallen asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

To make sure you can safely take Mirapex, tell your doctor if you have any of these other conditions:

  • low blood pressure;
  • kidney disease; or
  • tremors (dyskinesia) or uncontrolled muscle movements.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking Mirapex. It is not known whether the medicine actually causes this effect. Talk with your doctor if you believe you have any intense or unusual urges while taking Mirapex.

Some people taking Parkinson’s disease medications have developed skin cancer (melanoma). However, people with Parkinson’s disease may have a higher risk of melanoma. Talk to your doctor about this risk and what skin symptoms to watch for. You may need to have regular skin exams.

FDA pregnancy category C. It is not known whether Mirapex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Mirapex. It is not known whether pramipexole passes into breast milk or if it could harm a nursing baby. Do not use Mirapex without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction to Mirapex: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Mirapex and call your doctor at once if you have any of these serious side effects:

  • extreme drowsiness, falling asleep suddenly, even after feeling alert;
  • nausea, sweating, feeling light-headed, fainting;
  • hallucinations;
  • muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine;
  • chest discomfort, dry cough, feeling short of breath;
  • feeling weak or tired, loss of appetite, rapid weight loss;
  • fast or uneven heartbeats; or
  • tremors, twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

Less serious Mirapex side effects may include:

  • dry mouth, stomach pain, vomiting, constipation;
  • headache, dizziness, spinning sensation;
  • mild drowsiness;
  • swelling in your hands or feet;
  • appetite or weight changes;
  • blurred vision;
  • sleep problems (insomnia), unusual dreams;
  • amnesia, forgetfulness, thinking problems; or
  • impotence, loss of interest in sex, or trouble having an orgasm.

This is not a complete list of Mirapex side effects and others may occur. Call your doctor for medical advice about side effects.

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