Femara Side Effects

Femara (letrozole) lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Femara is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.

You should not use Femara if you are allergic to letrozole, or if you have not gone completely through menopause.

To make sure you can safely take Femara, tell your doctor if you have any of these other conditions:

  • osteoporosis;
  • high cholesterol; or
  • liver disease (especially cirrhosis).

FDA pregnancy category X. Femara can harm an unborn baby or cause birth defects. Do not use Femara if you are pregnant, or if you have not gone completely through menopause. Tell your doctor right away if you become pregnant during treatment. It is not known whether letrozole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine.

Get emergency medical help if you have any of these signs of an allergic reaction to Femara: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious Femara side effects may include:

  • dizziness, drowsiness, weakness, tired feeling;
  • hot flashes, warmth in your face or chest;
  • flushing (warmth, redness, or tingly feeling);
  • headache;
  • nausea, constipation;
  • bone pain, muscle or joint pain;
  • numbness, tingling, weakness, or stiffness in your hand or fingers;
  • pain in your hand that spreads to your arm, wrist, forearm, or shoulder;
  • night sweats; or
  • weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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