Atripla Side Effects

Atripla (efavirenz, emtricitabine, and tenofovir) is an antiviral medication that prevents human immunodeficiency virus (HIV) from reproducing in your body.

Atripla treats HIV in adults and children who are at least 12 years old. HIV causes acquired immunodeficiency syndrome (AIDS). This medication is not a cure for HIV or AIDS.

Do not use Atripla if you are pregnant. It could harm the unborn baby.

There are many other drugs that can cause serious or life-threatening medical problems if you take them together with Atripla. Tell your doctor about all medications you use.

Some people develop lactic acidosis while taking Atripla. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired. Atripla can cause severe or fatal liver problems. Call your doctor at once if you have symptoms such as nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Take Atripla exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Take Atripla on an empty stomach at bedtime.

To be sure this medicine is helping your condition, your blood will need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

If you have hepatitis B you may develop liver symptoms after you stop taking Atripla, even months after stopping. Your doctor may want to check your liver function for several months after you stop using the medication.

Atripla can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking Atripla.

Store Atripla in the original container at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Get emergency medical help if you have any of these signs of an allergic reaction to Atripla: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.

Stop using Atripla and call your doctor at once if you have any other serious side effects such as:

  • signs of liver damage – nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • urinating less than usual or not at all;
  • fever, chills, body aches, flu symptoms;
  • pale skin, feeling light-headed or short of┬ábreath, trouble concentrating;
  • rapid heart rate, increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia);
  • diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;
  • swelling in your neck or throat (enlarged thyroid);
  • weakness or prickly feeling in your fingers or toes;
  • problems with walking, breathing, speech, swallowing, or eye movement;
  • severe lower back pain, loss of bladder or bowel control;
  • unusual thoughts or behavior, anger, severe depression, thoughts of hurting yourself or others, hallucinations;
  • severe blistering, peeling, and red skin rash; or
  • seizure (convulsions).

Less serious Atripla side effects may include:

  • mild nausea, vomiting, gas, upset stomach;
  • headache, dizziness, drowsiness, strange dreams;
  • darkened skin on the palms of your hands or the soles of your feet; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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