Zetia Side Effects


Zetia (Ezetimibe) reduces the amount of cholesterol or other sterols that your body absorbs from your diet. Learn more about Zetia and Zetia Side Effects.

Zetia is used to treat high cholesterol, along with a low-fat, low-cholesterol diet. It is sometimes given with other cholesterol-lowering medications. It is also used to treat high blood sitosterol and campesterol along with diet therapy.

Zetia is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Some cholesterol medications should not be taken at the same time. Do not take Zetia with cholestyramine (Prevalite, Questran), colestipol (Colestid), or colesevelam (Welchol).

Wait at least 4 hours after taking any of these medicines before you take Zetia. You may also take Zetia 2 hours before taking any of these other medicines.

Zetia may be taken at the same time with fenofibrate (Antara, Lipofen, Lofibra, TriCor, Triglide), or with any of the “statin” drugs such as lovastatin (Mevacor), simvastatin (Zocor), pravastatin (Pravachol), fluvastatin (Lescol), atorvastatin (Lipitor), or cerivastatin (Baycol).

In rare cases, cholesterol-lowering medication can cause a condition that results in the breakdown of skeletal muscle tissue. This condition can lead to kidney failure. Call your doctor at once if you have unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine.

You should not use this medication if you are allergic to ezetimibe, or if you have liver disease.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Zetia:

  • kidney disease;
  • a thyroid disorder; or
  • if you use steroid medicine or hormones (including birth control pills).

In rare cases, cholesterol-lowering medication can cause a condition that results in the breakdown of skeletal muscle tissue. This condition can lead to kidney failure. Call your doctor at once if you have unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine.

FDA pregnancy category C. It is not known whether Zetia is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether ezetimibe passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Zetia Side Effects

Less serious Zetia side effects may include:

  • numbness or tingly feeling;
  • mild stomach pain, diarrhea;
  • tired feeling;
  • headache;
  • dizziness;
  • depressed mood;
  • runny or stuffy nose, cold symptoms;
  • joint pain, back pain; or
  • cough.

Call your doctor at once if you have a serious side effect such as:

  • unusual muscle weakness, tenderness, or pain;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • chest pain;
  • pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Get emergency medical help if you have any of these signs of an allergic reaction to Zetia: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

This is not a complete list of the Zetia side effects and others may occur. Call your doctor for medical advice about side effects.

If you think Zetia is right for you and would like to purchase some at a discounted rate online from an accredited Canadian Pharmacy go to CanadaDrugsDirect.com.


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