Ultram Side Effects


Ultram (tramadol) is a narcotic-like pain reliever.

Ultram is used to treat moderate to severe pain. Ultram extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock.

You should not take Ultram if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide.

Do not take Ultram while you are intoxicated (drunk) or taking any of the following:

  • alcohol or street drugs;
  • narcotic pain medicine;
  • sedatives or tranquilizers (such as Valium);
  • medicine for depression or anxiety; or
  • medicine for mental illness (such as bipolar disorder, schizophrenia).

Seizures have occurred in some people taking Ultram. Talk with your doctor about your seizure risk, which may be higher if you have:

  • a history of drug or alcohol addiction;
  • a history of epilepsy or other seizure disorder;
  • a history of head injury;
  • a metabolic disorder; or
  • if you are also taking an antidepressant, muscle relaxer, narcotic, antipsychotic, or medicine for nausea and vomiting.

To make sure you can safely take Ultram, tell your doctor if you have any of these other conditions:

  • kidney disease (or if you are on dialysis);
  • cirrhosis or other liver disease;
  • a stomach disorder; or
  • a history of depression, mental illness, or thoughts of suicide.

Ultram may be habit forming and should be used only by the person it was prescribed for. Never share Ultram with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category C. It is not known whether Ultram will harm an unborn baby. Ultram may cause serious or fatal side effects in a newborn if the mother uses this medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant while using Ultram. Tramadol can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Ultram. Do not give this medication to anyone younger than 16 years old without the advice of a doctor.

Get emergency medical help if you have any of these signs of an allergic reaction to Ultram: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Ultram and call your doctor at once if you have any of these serious side effects:

  • agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
  • seizure (convulsions);
  • a red, blistering, peeling skin rash; or
  • shallow breathing, weak pulse.

Less serious Ultram side effects may include:

  • dizziness, spinning sensation;
  • constipation, upset stomach;
  • headache;
  • drowsiness; or
  • feeling nervous or anxious.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


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