Hyaluronic Acid Side Effects
Hyaluronic acid, also known as hyaluronic sodium, is a substance which is normally found naturally in the human body. The highest concentrations of hyaluronic acid can be found in the eyes and joints. In the laboratory, hyaluronic acid is created to be used in medicine by extracting it from rooster combs or made by bacteria.
Normally, people will take hyaluronic acid for various types of joint disorders, including osteoarthritis. It can be taken orally or by injection from health care professionals.
The prescription forms of hyaluronic acid have been found to be safe for most people. Hyaluronic acid side effects are few. Some of the side effects are coughing, problems in swallowing, dizziness, fever and fainting. Other hyaluronic acid side effects are skin rashes and irritations, itching, and stuffy nose, swelling in the eyelids, face and lips, difficulty in breathing, diarrhea, acute headaches, and loss of appetite, nausea, stomach aches and swelling of the knees have also been reported. Sometimes there can be pain and redness where it has been injected. If hyaluronic acid has been used for eye surgery, there can be increased pressure in the eye. On rare occasions hyaluronic acid side effects may be allergic reactions.
There is special advice and warnings for pregnant and nursing mothers. Hyaluronic acid should not be taken by mouth or applied to the skin. If you are breast feeding, you should not use hyaluronic acid. It is not known if it can get into breast milk and what types of effects it might have on infants.
Recently there has been a lot of interest in using hyaluronic acid to prevent the effects of aging. It has been called the “fountain of youth”. However, there is not enough evidence at the time to support the claims that it should be used to prevent any of the changes that are often associated with aging. It is often used in plastic surgery as a lip filler.
Let’s review its potential medical uses- one. Osteoarthritis Hyaluronan preparations have shown to cut agony but improve the mobility of patients suffered from knee osteoarthritis. The improvement in the condition is possibly related to alternations in the synovial liquid viscoelasticity, cartilage metabolism, and swelling.  Turkish researchers injected high molecular weight hyaluronic acid ( Hylan G-F twenty ) and low molecular weight hyaluronic acid ( Orthovisc ) to 92 patients suffered from knee osteoarthritis separately at one-week intervals for 3 weeks. Both hyaluronic acid preparations led to a pronounced decrease in agony and improved function, without problems.  Roth An et al, Friedrich Schiller College Jena, Germany, treated rats with high molecular weight hyaluronic acid ( 1.7X10 ( six ) a ; 0.5 mg / dose ). They discovered that a short term hyaluronic acid treatment could repress acute swelling and cartilage damage while a long term hyaluronic acid treatment promote joint swelling, swelling and cartilage damage.  two. Brain Injury Tian WM et al, Tsinghua School , China, found hydrogel made from hyaluronic acid-poly-D lysine is compatible to rat brain tissue as this hydrogel has an open permeable structure and its viscoelastric properties are like the neural tissue’s.  three. Skin Conditions licensing permission in the United States, Canada and Europe was given latterly for 3 p.c. diclofenac in 2.5% HA gel, Solaraze ( R ), for the topical treatment of actinic keratoses, which is the 3rd commonest skin complaint in the States. The gel is well endured, safe and efficient and provides an interesting, inexpensive alternative choice to cryoablation, curettage or dermabrasion, or treatment with 5-fluorouracil.
 four. Appearance – Wrinkles and Folds This injectable Restylane ( hyaluronic acid ) gel was given approval on March twenty-five, 2005. It’s a clear hyaluronic acid gel that is injected into facial tissue to smooth wrinkles and folds, particularly round the nose and mouth ( nasolabial folds ).
This hyaluronic acid gel works by briefly adding volume to facial tissue to restore a smoother appearance to the face. The effects of this hyaluronic acid gel can go on for about six months. In a controlled study, most patients required one injection of this hyaluronic acid gel to gain the best advantages of wrinkle smoothing ; about one in three of patients required more than one injection of this hyaluronic acid gel to get an acceptable result.  The complications of Hyaluronic Acid Hyaluronic acid was well-tolerated in a demonstrative treatment for knee osteoarthritis. The share of complications is about 2.5%..  Petrella RJ.
Performed three-intraarticular injection series with Suplasyn ( ten mg / ml, 2-ml injection ) to patients suffered from knee osteoarthritis over three weeks.
Dr. Petrella noted complications restricted to local discomfort and swelling.  In geneal, side-effects of hyaluronic acid gel include bruising, rosiness, swelling, agony, sensitivity and itching additionally, hyaluronic acid gel shouldn’t be employed in patients suffered from serious allergies. .